Mononuclear Phagocytes

Among the cells originating in the bone marrow, the mononuclear phagocytes constitute a separate cell line.

Mononuclear Phagocytes

The term mononuclear phagocyte covers a group of cells including the macrophages in the tissues and the ancestors of these cells, i. e. , the monocytes in the peripheral blood, and their precursors in the bone marrow, the promonocytes and monoblasts. Among the cells originating in the bone marrow, the mononuclear phagocytes constitute a separate cell line. The effector cell of this line is the macrophage, which plays an important role in the host defence against infective agents and neoplastic cells as well as in the removal of antigens, antigen-antibody complexes, effete cells, and damaged tissues. Metchnikoff ( r 892) was the first to describe the macrophage and the microphage, the latter now being called polymorphonuclear leucocyte or granulocyte, and to recognize that phagocytes not only serve as scavengers, but also play an important role in the host defence against micro-organisms. However, Haeckel ( r862) had made the first observa tion of endocytosis 30 years before. In his book 'Die Radiolaren' published in r862, Haeckel wrote: I first observed this phenomenon in May, 1859, in a specimen of Thetis fimbria, which I had injected with an aqueous suspension of fine Indigo particles in connection with a study of the vascular system.

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Mononuclear Phagocytes
Language: en
Pages: 1961
Authors: R. van Furth
Categories: Medical
Type: BOOK - Published: 2014-08-23 - Publisher: Springer

The term mononuclear phagocyte covers a group of cells including the macrophages in the tissues and the ancestors of these cells, i. e. , the monocytes in the peripheral blood, and their precursors in the bone marrow, the promonocytes and monoblasts. Among the cells originating in the bone marrow, the
Mononuclear Phagocytes
Language: en
Pages: 830
Authors: R. van Furth
Categories: Medical
Type: BOOK - Published: 2011-10-02 - Publisher: Springer

Sixteen years have passed since the first Leiden Conference on Mononuclear Phagocytes. That first meeting led to new nomenclature, i. e. , the Mononuclear Phagocytes System (MPS), which was published in the Bulletin of the World Health Organization (R. van Furth, et aI. , Bull. WHO, 1972, 46: 845-852). The
The Multiplication of Mycobacterium Tuberculosis Within Mononuclear Phagocytes of Experimental Animals
Language: en
Pages: 134
Authors: ALBERT ARCHER GROVER
Categories: Mycobacterium tuberculosis
Type: BOOK - Published: 1954 - Publisher:

Books about The Multiplication of Mycobacterium Tuberculosis Within Mononuclear Phagocytes of Experimental Animals
Mononuclear Phagocytes
Language: en
Pages: 668
Authors: R. van Furth
Categories: Medical
Type: BOOK - Published: 2013-04-17 - Publisher: Springer Science & Business Media

Mononuclear phagocytes, which include macrophages, monocytes and their precursor cells, are the most important cells in the host defence against micro-organisms and tumor cells. During the last twenty-five years research on the biology of mononuclear phagocytes has increased tremendously. This motivated Professor R. van Furth to organize five international conferences
Methods for Studying Mononuclear Phagocytes
Language: en
Pages: 1048
Authors: Dolph Adams
Categories: Science
Type: BOOK - Published: 2012-12-02 - Publisher: Elsevier

Methods for Studying Mononuclear Phagocytes is a practical guide to the study of mononuclear phagocytes that brings together various well-established and useful methods for examining these cells. The technical protocols have been made detailed, specific, practical, and inclusive of the necessary mystique for immediate and direct application in the laboratory.